Thermodynamically Controlled Deracemization Utilizing Inclusion Complexation
نویسندگان
چکیده
منابع مشابه
Inclusion Complexation: Liquid Chromatography
Liquid chromatography (LC) may be simply described as an analytical technique used to separate the individual components of a solution based on their relative afRnities for a liquid mobile phase and a stationary phase. There are numerous modes of LC (i.e. reversed-phase, normal-phase, ion exchange) that are commonly classiRed according to the mechanism by which separation occurs. One such mecha...
متن کاملIs protein turnover thermodynamically controlled?
A parametric correlation (p less than 0.01) has been found between the in vitro thermal stability and in vivo turnover rates of nine intracellular proteins. These results are discussed in terms of a "thermodynamic" model for turnover control, in which the rate of intracellular protein degradation is controlled by intramolecular conformation equilibria. A peculiar exception is provided by glycer...
متن کاملSupramolecular templating in thermodynamically controlled synthesis.
T perspective has a simple message: Covalent synthesis under thermodynamic control can be a powerful tool for preparing mechanically interlocked structures and specific macrocycles in high yield and at the same time serve as an engine for the creation of dynamic combinatorial libraries (DCLs), which are responsive to their environment. Here we will highlight some examples that illustrate the po...
متن کاملCarvedilol Solubility Enhancement by Inclusion Complexation and Solid Dispersion: Review
Carvedilol is an effective nonselective alpha-1 and beta blocker discovered by Fritz Wiedemann [1] . It is an antihypertensive drug indicated for the treatment of mild to severe congestive heart failure (CHF), angina pectoris, cardiac arrhythmias and myocardial infarction [2] . Water solubility of Carvedilol is a fundamental property that affects the drug absorption after oral administration. M...
متن کاملSurface modification of polymeric vesicles via host-guest inclusion complexation.
We have prepared a novel kind of building block (CD-PI-CD) of polyether imide (PI) with beta-cyclodextrin (beta-CD) at the both ends that self-assembles into vesicles in water. The vesicles are "reactive" in supramolecular chemistry because the host groups of beta-CD equally distribute on the inside and outside surfaces of the vesicles. Isothermal titration calorimetry (ITC) and static light sc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2008
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.128.1431